Performance of Multitarget Stool DNA Testing in African American Patients – Cooper – – Cancer


Background

Multitarget stool DNA (mt‐sDNA) is an approved method for colon cancer screening that is especially relevant for patients who cannot undergo colonoscopy. Although the test performance has been evaluated in a large clinical trial, it was limited to a predominantly white population. Given differences in the epidemiology and biology of colon cancer in African American individuals, the authors sought to compare the performance of mt‐sDNA between racial groups.

Methods

The authors prospectively identified patients aged ≥40 years who were referred for colonoscopy at an academic medical center and 2 satellite facilities….

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