Alzheimer’s pathophysiology shows racial disparities

A new study conducted at Washington University School of Medicine has identified racial disparities between African-Americans and Caucasians in the way in which Alzheimer’s disease arises and develops.

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African-Americans are more likely to develop the disease than Caucasian Americans, but researchers do not know why, since studies have generally focused on white participants.

Now, Dr. John Morris and team have discovered key differences in levels of a protein that has been implicated in Alzheimer’s disease.

Specifically, the study suggests that African-Americans tend to have lower levels of the brain protein tau, meaning they may not meet the threshold for diagnosis once the disease has already started to develop in their brains.

As reported in the…

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